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Related Concept Videos

Analgesia and Pain Management01:25

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
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Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
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Peripheral Neuromodulation for Chronic Pain.

Milind Deogaonkar1

  • 1Department of Neurosurgery, West Virginia University Health Sciences Center, Morgantown, WV, USA.

Neurology India
|December 15, 2020
PubMed
Summary
This summary is machine-generated.

Peripheral neuromodulation, specifically peripheral nerve field stimulation (PNFS), offers an effective, minimally invasive treatment for chronic neuropathic pain. This targeted approach is increasingly utilized for localized pain management.

Keywords:
Chronic painface painfield stimulationfocal painheadachemigrainenerve stimulationneuropathic painperipheral neuromodulationpost-herpatic neuralgia

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Area of Science:

  • Neurology
  • Pain Management
  • Neurosurgery

Background:

  • Chronic focal neuropathic pain presents significant treatment challenges.
  • Conventional treatments like nerve blocks offer limited efficacy and duration.
  • Existing neuromodulation techniques (e.g., SCS) are invasive and affect broad areas.

Purpose of the Study:

  • To review the indications for peripheral neuromodulation.
  • To detail the technique, programming, and nuances of peripheral neuromodulation.
  • To discuss the outcomes associated with peripheral neuromodulation.

Main Methods:

  • Comprehensive review of published literature on peripheral neuromodulation.
  • Analysis of the author's clinical experience with over 500 peripheral neuromodulation cases.

Main Results:

  • Peripheral nerve field stimulation (PNFS) demonstrates effectiveness in treating neuropathic pain.
  • PNFS is a minimally invasive and targeted neuromodulation modality.
  • The utilization of PNFS is increasing in clinical practice.

Conclusions:

  • Peripheral neuromodulation, particularly PNFS, is a viable and effective treatment option.
  • PNFS provides a targeted solution for localized neuropathic pain.
  • This modality represents a growing advancement in pain management.