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Updated: Nov 25, 2025
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
The challenge of primary gastric melanoma: a systematic review
Gregory S Mellotte1,2, Diya Sabu3, Mary O'Reilly1
1Department of Gastroenterology, Tallaght University Hospital, Dublin, D24 NR04, Ireland.
Aim:
Primary gastric melanoma is a rare clinical presentation. The purpose of this review was to compare the 1-year survival in patients who underwent surgery with patients who did not receive treatment.
Patients & Methods:
A systematic search of databases for case reports and case series of primary gastric melanoma was conducted.
Results:
The mean survival of patients was 22 months. One-year survival was 56.5% with surgery, rising to 66% with adjuvant therapy. Mean survival of the surgical group was 21.05 months (±20.2) versus 4.5 months (±3.61) in the nonsurgical group.
Conclusion:
Primary gastric melanoma has a poor prognosis but early surgical intervention can have a significant impact on patient outcome. We reviewed the biology and clinical diagnosis of gastrointestinal melanoma and the current management options available.
