Related Experiment Video For anal intraepithelial neoplasia
Updated: Nov 25, 2025
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
Opportunistic detection of anal intraepithelial neoplasia at colonoscopy
Clara M Forbes1, Jenny McCloskey1,2, Geoffrey M Forbes1
1School of Health and Medical Sciences University of Western Australia Perth Western Australia Australia.
Background And Aim:
Human papilloma virus-associated anal intraepithelial neoplasia (AIN) precedes most anal cancers and can be detected at colonoscopy. We aimed to quantify AIN detection rates in a general population undergoing colonoscopy.
Methods:
A retrospective review of a community-based practice for 2 years until December 2019 was conducted.
Results:
A total of 2525 patients (1051 males and 1474 females; median age 59 years) had 2608 colonoscopies. Ten patients (two males and eight females; median age 57.5 years) had incidentally detected AIN (condyloma acuminatum or AIN1, n = 4; AIN2 or 3, n = 6). AIN was detected in 1 of 261 (95% CI 1/142-1/480) colonoscopies and 1 of 163 (95% CI 1/83-1/321) colonoscopies in women over 40 years old.
Conclusions:
Opportunistically detecting AIN, especially in women over 40 years old, should be an important adjunct to colonoscopy-based colorectal neoplasia detection.
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