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Related Concept Videos

Endoscopic Procedures III: Video Capsule Endoscopy01:28

Endoscopic Procedures III: Video Capsule Endoscopy

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Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
456
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Related Experiment Video

Updated: Nov 25, 2025

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
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Immune checkpoint inhibitor-induced enteritis assessed using capsule endoscopy.

Shinsuke Otagiri1, Takehiko Katsurada1, Kana Yamanashi1

  • 1Department of Gastroenterology and Hepatology Hokkaido University Graduate School of Medicine Sapporo Japan.

JGH Open : an Open Access Journal of Gastroenterology and Hepatology
|December 15, 2020
PubMed
Summary

Capsule endoscopy effectively evaluated immune checkpoint inhibitor-induced enteritis, revealing small intestinal ulcers. This case highlights capsule endoscopy as a valuable tool for managing these specific gastrointestinal adverse events.

Keywords:
capsule endoscopyimmune‐related adverse eventintestinal disorder

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Area of Science:

  • Gastroenterology
  • Oncology
  • Pharmacology

Background:

  • Immune checkpoint inhibitors (ICIs) are crucial cancer therapies.
  • ICI-induced enteritis is a significant adverse event.
  • Diagnostic methods for ICI-induced enteritis require further evaluation.

Purpose of the Study:

  • To assess the utility of capsule endoscopy in diagnosing immune checkpoint inhibitor-induced enteritis.
  • To report a case of successful capsule endoscopy use for ICI-induced gastrointestinal adverse events.

Main Methods:

  • Capsule endoscopy was performed on a patient with suspected immune checkpoint inhibitor-induced enteritis.
  • Findings were analyzed to identify gastrointestinal lesions.

Main Results:

  • Capsule endoscopy revealed multiple erosions and small ulcers in the small intestine.
  • No prior reports demonstrated capsule endoscopy's effectiveness for ICI-induced gastrointestinal adverse events.

Conclusions:

  • Capsule endoscopy may be a useful diagnostic tool for immune checkpoint inhibitor-induced enteritis.
  • This case supports the role of capsule endoscopy in evaluating ICI-related gastrointestinal toxicity.