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Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
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Relation between Maternal and Neonatal Serum Lipid Profile and Their Impact on Birth Weight

Tamer A Abdel-Hamid1, Dalia AbdelLatif1, Eman Ahmed2

  • 1Pediatrics Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

American Journal of Perinatology
|December 15, 2020
PubMed

Insights

Maternal malnutrition impacts infant lipid profiles and birth weight. Lower lipid levels were observed in small for gestational age infants, with correlations found between maternal and neonatal lipids and birth weight.

Area of Science:

  • Perinatal Medicine
  • Neonatal Nutrition
  • Lipid Metabolism

Background:

  • Maternal malnutrition and altered lipid metabolism during pregnancy can affect fetal development.
  • Understanding the maternal-fetal lipid connection is crucial for assessing birth outcomes.

Purpose of the Study:

  • To investigate the relationship between maternal and neonatal serum lipid profiles.
  • To compare lipid profiles between small for gestational age (SGA) and appropriate for gestational age (AGA) infants.
  • To determine the impact of maternal malnutrition on birth weight.

Main Methods:

  • A cross-sectional study involving 150 pregnant women.
  • Maternal serum lipid profiles (HDL, LDL, TGs, total cholesterol) measured before delivery.
  • Neonatal cord blood lipid profiles and birth weights assessed post-delivery, categorizing neonates into SGA and AGA groups.

Main Results:

  • Small for gestational age (SGA) neonates exhibited lower serum levels of LDL, TGs, and total cholesterol compared to appropriate for gestational age (AGA) neonates.
  • A positive correlation was observed between maternal and neonatal serum triglyceride levels.
  • Birth weight showed a positive correlation with maternal serum LDL, TGs, and total cholesterol levels.

Conclusions:

  • Maternal serum lipid profile serves as a potential indicator for neonatal lipid profile and birth weight.
  • Findings highlight the influence of maternal lipid status on fetal growth and neonatal lipid parameters.
Abstract

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