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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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Protein intake and renal function in older patients.
Yoko Narasaki1, Connie M Rhee1, Holly Kramer2,3,4
1Division of Nephrology, Hypertension and Kidney Transplantation, Harold Simmons Center for Chronic Disease Research and Epidemiology, University of California Irvine, Orange, California.
Current Opinion in Clinical Nutrition and Metabolic Care
|December 16, 2020
Summary
Managing dietary protein intake (DPI) is crucial for elderly patients with chronic kidney disease (CKD). A plant-dominant low-protein diet can help preserve kidney function and prevent protein-energy wasting (PEW) in this population.
Area of Science:
- Nephrology
- Geriatrics
- Nutritional Science
Background:
- Chronic kidney disease (CKD) is common in older adults, often accompanied by age-related kidney changes and comorbidities like hypertension.
- Dietary protein intake (DPI) significantly impacts kidney health and survival in elderly individuals with CKD.
Purpose of the Study:
- To review the effects of DPI on kidney health and survival in older CKD patients.
- To evaluate the role of dietary protein management in this demographic.
Main Methods:
- Literature review focusing on DPI, kidney function, and survival in elderly CKD patients.
- Analysis of current recommendations for protein intake and nutritional strategies.
Main Results:
- Kidney compensatory mechanisms for increased DPI decline with age, with compensation preserved up to 80 years.
- Long-term high DPI can accelerate kidney function decline in older adults with or without CKD.
- Prescribing plant-dominant low-protein diets (0.6-0.8 g/kg/day) or very low protein diets (<0.45 g/kg/day) with supplements may preserve kidney function.
- Monitoring for protein-energy wasting (PEW) is essential when implementing protein-restricted diets.
Conclusions:
- Tailored, plant-dominant low-DPI strategies, ensuring adequate energy and nitrogen balance, can mitigate kidney function decline in elderly CKD patients.
- Precision nutrition approaches are key to preventing PEW while managing kidney health in this population.
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