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Moving the Dial on Heart Failure Patient Adherence Rates
Eleanna Makris1, Lucy Hu1, Graham B Jones1,2
1TRD Innovation Group, Novartis Pharmaceuticals, East Hanover, NJ 07936, USA.
Patient Preference and Adherence
|December 16, 2020
Summary
Improving heart failure treatment adherence is crucial for reducing patient mortality and healthcare costs. Multi-factor interventions, tailored to patient personas, show the most promise for enhancing adherence and improving outcomes.
Area of Science:
- Cardiology
- Health Services Research
- Patient Adherence
Background:
- Heart failure significantly impacts global morbidity and mortality.
- Patients face challenges adhering to complex treatment regimens due to physical and social factors.
Purpose of the Study:
- To review factors contributing to low heart failure treatment adherence.
- To propose single- and multi-factor interventions for improved patient management.
Main Methods:
- A narrative review of primary literature from 2015-2020 was conducted.
- Identified adherence barriers were mapped to potential solutions.
Main Results:
- Adherence can be enhanced through single-factor solutions (e.g., electronic reminders, education, incentives, gamification, community support, persona-based modeling, polypharmacy burden relief).
- Multi-factor solutions combine multiple approaches for tailored, flexible interventions.
Conclusions:
- Poor adherence in heart failure patients leads to increased mortality, hospitalizations, and costs.
- Multi-factor solutions offer the broadest potential for improving adherence.
- Patient personas are key to developing effective interventions, with potential applications in clinical trials.
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