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Sleep during menopausal transition: a 10-year follow-up.
Nea Kalleinen1,2, Jenni Aittokallio1,3,4, Laura Lampio1,5
1Department of Pulmonary Diseases and Clinical Allergology, Sleep Research Center, University of Turku, Turku, Finland.
Sleep
|December 16, 2020
Summary
Sleep architecture in middle-aged women remains stable over ten years, with changes primarily linked to aging, not the menopausal transition. Polysomnography (PSG) data showed age-related shifts, not menopause-related decline in sleep quality.
Area of Science:
- Sleep medicine
- Reproductive endocrinology
- Gerontology
Background:
- The menopausal transition significantly impacts women's health.
- Sleep disturbances are common during midlife.
- Understanding sleep architecture changes is crucial for women's well-being.
Purpose of the Study:
- To evaluate changes in sleep architecture over a 10-year period in premenopausal women.
- To determine the influence of the menopausal transition and aging on sleep patterns.
Main Methods:
- A 10-year observational follow-up study of 57 premenopausal women.
- Polysomnography (PSG) and serum follicle-stimulating hormone (S-FSH) measurements at baseline and follow-up.
- Linear regression analysis to assess the effects of aging and S-FSH levels on sleep.
Main Results:
- Higher S-FSH levels correlated with longer sleep latency.
- Ten years of aging were associated with shorter sleep latency and latency to stage 2 sleep.
- Aging also led to decreased stage 2 sleep and increased slow-wave sleep.
Conclusions:
- Sleep architecture in middle-aged women does not worsen due to the menopausal transition over a decade.
- Observed sleep changes are predominantly age-dependent rather than menopause-dependent.
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