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Direct Mouse Trauma/Burn Model of Heterotopic Ossification

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Published on: August 6, 2015

Heterotopic ossification after local steroid injection.

Sean S Li¹, Suellen S Li², Reid A Abrams³

¹Department of Surgery, Division of Plastic Surgery, UC San Diego, San Diego, California, USA.

BMJ Case Reports

|December 17, 2020

Summary

Pachydermodactyly (PDD) treatment with steroid injections led to unexpected heterotopic ossification. This case highlights a new potential complication of local steroid injections, previously unlinked to PDD.

Keywords:

dermatology orthopaedics plastic and reconstructive surgery

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Area of Science:

Rheumatology
Orthopedics
Dermatology

Background:

Pachydermodactyly (PDD) is a rare, benign condition causing progressive swelling of hand phalangeal joints.
Local steroid injections are a common treatment for PDD symptoms.

Observation:

A 37-year-old man with PDD received local steroid injections for joint swelling.
Following treatment, the patient developed heterotopic ossification and para-articular calcifications at the injection sites.

Findings:

Heterotopic ossification is not a known complication of Pachydermodactyly.
This is the first reported instance of heterotopic ossification occurring after local steroid injection.

Implications:

This case suggests a novel potential complication associated with local steroid injections.
Further investigation is warranted to understand the mechanism and incidence of this adverse event.