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Legionella infections.

W T Ching1, R D Meyer

  • 1Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine.

Infectious Disease Clinics of North America
|September 1, 1987
PubMed
Summary
This summary is machine-generated.

Legionnaires

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Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Legionnaires' disease, a severe pneumonia, is caused by Legionella pneumophila.
  • The bacterium was first isolated in 1947, preceding its identification during a 1976 epidemic.
  • Numerous Legionella species exist, often causing infections indistinguishable from L. pneumophila.

Purpose of the Study:

  • To review the clinical entity of Legionnaires' disease.
  • To discuss the causative agent, Legionella pneumophila.
  • To highlight the historical context and broader spectrum of Legionella infections.

Main Methods:

  • Literature review of historical and scientific records.
  • Analysis of clinical and microbiological data related to Legionella.

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  • Epidemiological investigation of disease outbreaks.

    • Main Results:

    • Legionella pneumophila identified as the primary cause of Legionnaires' disease.
    • The bacterium's initial isolation predates the 1976 epidemic.
    • Other Legionella species can cause similar pneumonia and non-pneumonic illness (Pontiac Fever).

    Conclusions:

    • Legionnaires' disease is a significant public health concern caused by Legionella.
    • The spectrum of Legionella includes Pontiac Fever and extrapulmonary infections.
    • Understanding Legionella's diverse manifestations is crucial for diagnosis and control.