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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

118
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
118
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

130
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
130
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

170
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
170
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

94
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
94
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

184
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
184
Mitral Valve Prolapse I: Introduction01:27

Mitral Valve Prolapse I: Introduction

170
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
170

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Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
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Indirect Mitral Annuloplasty Using the Carillon Device.

Amar Krishnaswamy1, Samir R Kapadia2

  • 1Department of Interventional Cardiology, Cleveland Clinic, Cleveland, OH, United States.

Frontiers in Cardiovascular Medicine
|December 17, 2020
PubMed
Summary
This summary is machine-generated.

Functional mitral regurgitation (FMR) patients can benefit from the Carillon device, an indirect annuloplasty. This percutaneous approach offers a safe alternative to surgery with promising clinical and echocardiographic results.

Keywords:
carillonheart failureindirect mitral annuloplastymitral regurgitationpercutaneous mitral valve repair

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Area of Science:

  • Cardiovascular medicine
  • Interventional cardiology
  • Medical devices

Background:

  • Functional mitral regurgitation (FMR), also known as secondary mitral regurgitation (SMR), significantly impacts patient health, leading to decline, hospitalization, and mortality.
  • Traditional mitral annuloplasty surgery, while effective, carries risks and concerns regarding long-term durability.
  • Percutaneous strategies present a valuable alternative for managing FMR.

Purpose of the Study:

  • To evaluate the efficacy and safety of the Carillon device for indirect mitral annuloplasty in patients with FMR.
  • To assess the device's impact on echocardiographic parameters and clinical outcomes.
  • To determine the feasibility and complication rates associated with the Carillon device implantation.

Main Methods:

  • The Carillon device employs the coronary sinus-mitral annulus relationship to perform an indirect annuloplasty.
  • Implantation technique is described as relatively straightforward.
  • Data from early series and recent randomized trials were analyzed.

Main Results:

  • The Carillon device demonstrated echocardiographic and clinical benefits in patients with FMR.
  • The implantation procedure was associated with a low rate of significant complications.
  • Evidence suggests a positive impact on patient outcomes.

Conclusions:

  • The Carillon device offers a promising percutaneous alternative for treating functional mitral regurgitation.
  • The device shows potential for improving patient symptoms and functional status.
  • Its straightforward technique and low complication rate make it an attractive option for FMR management.