Implant framework misfit: A systematic review on assessment methods and clinical complications

The fit of implant-supported prostheses is of prime importance for the long-term success of implant therapy.

This systematic review aimed to evaluate recent evidence on current techniques for assessing implant-framework misfit, its associated strain/stress, and whether these misfits are related to mechanical, biological, and clinical consequences.

An electronic search for publications from January 2010 to October 2020 was performed using the Pubmed, Embase, Web of Science, and Cochrane Library databases with combined keywords on implant-framework misfit assessments and related clinical complications. Inclusion and exclusion criteria were applied. After full-text analyses, data extraction was implemented on current techniques of misfit assessment and the relationship between the misfit and the induced strain/stress.

A total of 3 in vivo and 92 in vitro studies were selected, including 47 studies on quantifying the degree of implant-framework misfit with dimensional techniques, 24 studies measuring misfit-induced strain/stress with modeling techniques, and 24 studies using both methods. The technical details, advantages, and limitations of each technique were illustrated. The correlation between the implant-framework misfit and the induced strain/stress has been revealed in vitro, while that with the biological complications and implant/prostheses failure was weak in clinical studies.

Dimensional and modeling techniques are available to measure the implant-framework misfit. The passivity of implant-supported fixed prostheses appeared related to the induced strain/stress, but not the clinical complications. Further studies combining three-dimensional (3D) assessments using dimensional and modeling techniques was needed.