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Updated: Nov 25, 2025

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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IMPACT OF KRAS MUTATIONS IN CLINICAL FEATURES IN COLORECTAL CANCER

Renato Morato Zanatto1, Gianni Santos2, Júnea Caris Oliveira1

  • 1Department of Abdominal and Pelvic Surgery, Hospital Amaral Carvalho, Jaú, SP, Brazil.

Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery
|December 17, 2020
PubMed
Summary

KRAS mutations, found in nearly half of colorectal cancer patients, correlate with higher CEA levels and spread to multiple sites. Colon cancer with KRAS mutations indicates poorer survival.

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