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Updated: Nov 25, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Diastolic dysfunction for nephrologists: diagnosis at the point of care
Marcus G Bastos1,2,3, Ana Luisa Vieira4, José M Pazeli4
1Faculdade de Medicina da Universidade Federal de Juiz de Fora, MG, Brasil.
Insights
Early echocardiography for diastolic dysfunction in chronic kidney disease (CKD) can improve patient outcomes. Point-of-care diagnosis of this heart condition is key to preventing heart failure progression.
Area of Science:
- Nephrology
- Cardiology
- Echocardiography
Background:
- Cardiovascular diseases are a leading cause of death in chronic kidney disease (CKD) patients.
- Diastolic dysfunction (DD) often precedes heart failure with preserved ejection fraction in CKD.
- Early detection of DD is crucial for improving CKD prognosis.
Purpose of the Study:
- To review diastolic dysfunction in kidney disease.
- To present a practical approach for point-of-care echocardiographic diagnosis of DD in CKD patients.
Main Methods:
- Literature review on DD in CKD.
- Focus on echocardiographic diagnostic methods for point-of-care application.
Main Results:
- Diastolic dysfunction is prevalent in CKD and linked to adverse cardiovascular outcomes.
- Echocardiography enables early identification of DD.
- Point-of-care diagnosis facilitates timely intervention.
Conclusions:
- Early echocardiographic identification of DD in CKD is feasible and important.
- Timely treatment based on early diagnosis can improve outcomes for CKD patients.
- A practical approach to point-of-care echocardiography aids in managing cardiovascular risk in CKD.
Abstract:
Cardiovascular diseases are important causes of morbidity and mortality in the course of chronic kidney disease (CKD). Diastolic dysfunction (DD) may progress with the clinical manifestation of heart failure, known as heart failure with preserved ejection fraction, a condition that precedes systolic dysfunction. The early identification of DD by echocardiography at the point-of-care before the appearance of symptoms and signs of pulmonary congestion and the implementation of appropriate treatment can improve the prognosis of CKD. This review article briefly addresses DD in kidney disease and presents a practical approach to the echocardiographic diagnosis of DD at the point of care.
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