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Updated: Nov 25, 2025
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Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
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[A woman with a bleeding umbilical nodule]
Jade Smorenburg1, Mark D van der Laan2, Kim A B M Pruissen-Peeters3,4
1St. Antonius Ziekenhuis, afd. Dermatologie,Nieuwegein.
Nederlands Tijdschrift Voor Geneeskunde
|December 17, 2020
Summary
A bleeding umbilical nodule in a woman was initially suspected to be a Sister Mary Joseph
Area of Science:
- Dermatology
- Gynecology
- Pathology
Background:
- Umbilical nodules can present diagnostic challenges.
- Sister Mary Joseph's nodule indicates metastasis, necessitating a thorough differential diagnosis.
Observation:
- A 39-year-old woman presented with a bleeding umbilical nodule.
- The clinical presentation raised suspicion for malignancy.
Findings:
- Punch biopsy confirmed the nodule was cutaneous endometriosis.
- This finding excluded metastatic disease.
Implications:
- Cutaneous endometriosis should be considered in the differential diagnosis of umbilical lesions.
- Accurate diagnosis prevents unnecessary oncologic workup.
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