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Related Concept Videos

Micelles01:30

Micelles

Micelle formation is an intricate process that hinges on the properties of amphiphilic or amphipathic molecules and the conditions of the system in which they are found. Amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, play a critical role in this process.In aqueous environments, these molecules arrange themselves such that their hydrophilic heads are turned towards the water phase, while their hydrophobic tails are oriented away...

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Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
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Stimuli-Responsive Zwitterionic Core-Shell Microgels for Antifouling Surface Coatings.

Pabitra Saha1,2, Marta Santi1,2, Meike Emondts1,2

  • 1DWI-Leibniz-Institute for Interactive Materials, Aachen 52056, Germany.

ACS Applied Materials & Interfaces
|December 17, 2020
PubMed
Summary

This study introduces a novel dual stimuli-responsive antifouling microgel coating for membranes. The polyzwitterion-enriched system effectively repels proteins and prevents biofouling, showing promise for advanced filtration and drug delivery applications.

Keywords:
antifoulingantipolyelectrolytemembrane coatingmicrogelpolyzwitterion

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Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Surface Science

Background:

  • Membrane fouling, caused by non-specific interactions, significantly limits filtration efficiency in various applications.
  • Developing advanced antifouling coatings is crucial for enhancing membrane performance and longevity.

Purpose of the Study:

  • To establish a facile method for coating membrane surfaces with a dual stimuli-responsive antifouling microgel system.
  • To create a microgel system enriched with high polyzwitterion content for superior antifouling properties.

Main Methods:

  • Synthesis of poly(sulfobetaine) (PSB) zwitterionic polymers using reversible addition-fragmentation chain transfer (RAFT) polymerization.
  • Integration of PSB onto poly(N-vinylcaprolactam) (PVCL) microgels via precipitation polymerization to form a core-shell microstructure.
  • Characterization using cryogenic transmission electron microscopy (Cryo-TEM) and temperature-dependent 1H NMR spectroscopy.
  • Evaluation of antifouling properties using quartz crystal microbalance with dissipation monitoring (QCM-D) on functionalized poly(ethersulfone) membranes.

Main Results:

  • A core-shell microgel morphology with a PVCL-rich core and a PSB-rich shell was successfully fabricated.
  • The microgels exhibited dual stimuli-responsive behavior, with tunable phase transition temperatures and antipolyelectrolyte effects in response to temperature and NaCl concentration.
  • Functionalized membranes demonstrated significant protein-repelling properties, with enhanced performance at higher NaCl concentrations.
  • The microgel coatings effectively prevented biofouling on model poly(ethersulfone) membranes.

Conclusions:

  • The developed dual stimuli-responsive zwitterionic microgel system offers a promising strategy for creating advanced antifouling surfaces.
  • These microgels can be utilized as effective protein-repelling coatings, enhancing membrane performance in saline environments.
  • The stimuli-responsive nature of the microgels also suggests potential applications in temperature-triggered drug delivery systems.