[Mortality and re-admission after hospitalization with COVID-19]

Wouter T Leijte1, Nicolaas M M Wagemaker1, Tom D A van Kraaij2

  • 1Zuyderland Medisch Centrum, afd. Longziekten, Sittard/Heerlen.

Insights

One in six patients hospitalized with COVID-19 experienced death or readmission post-discharge. This highlights ongoing patient vulnerability and the need for careful discharge planning and monitoring for coronavirus disease 2019 survivors.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Epidemiology

Background:

  • Hospitalization for coronavirus disease 2019 (COVID-19) can lead to post-discharge complications.
  • Understanding outcomes after COVID-19 hospitalization is crucial for patient management.

Purpose of the Study:

  • To evaluate mortality rates and readmission characteristics following COVID-19 hospitalization.
  • To identify risk factors associated with death and readmission after discharge.

Main Methods:

  • Retrospective cohort study of 769 patients hospitalized with COVID-19.
  • Analysis included in-hospital mortality, post-discharge mortality, and readmission rates.
  • Regression analysis was used to determine risk factors for adverse outcomes.

Main Results:

  • In-hospital mortality was 22.4%. Post-discharge mortality was 6.4% and the readmission rate was 11.7%.
  • Leading causes for readmission included respiratory insufficiency, thrombotic events, and chronic comorbidities.
  • Older age, delirium during hospitalization, male sex, discharge to long-term care, and COPD were associated with increased mortality or readmission.

Conclusions:

  • Approximately 1 in 6 COVID-19 patients faced death or readmission after discharge.
  • This indicates a sustained vulnerability in COVID-19 survivors, necessitating informed discharge strategies and ongoing monitoring.
  • Findings support the need for proactive hospital capacity planning and patient follow-up protocols.
Abstract

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