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Updated: Nov 25, 2025

A Multimodal Imaging Framework to Advance Phenotyping of Living Label-free Breast Cancer Cells
Published on: August 22, 2025
Coherent anti-Stokes Raman scattering imaging of microcalcifications associated with breast cancer
Georgi I Petrov1, Rajan Arora, Vladoslav V Yakovlev
1Department of Biomedical Engineering, Texas A&M University, College Station, TX 77843, USA. yakovlev@tamu.edu.
Abstract:
Chemical imaging of calcifications was demonstrated in the depth of a tissue. Using long wavelength excitation, broadband coherent anti-Stokes Raman scattering and hierarchical cluster analysis, imaging and chemical analysis were performed 2 mm below the skin level in a model system. Applications to breast cancer diagnostics and imaging are discussed together with the methods to further extend the depth and improve the spatial resolution of chemical imaging.
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