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Related Experiment Video

Updated: Nov 25, 2025

Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels
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Transcranial brain atlas-based optimization for functional near-infrared spectroscopy optode arrangement: Theory,

Yang Zhao1, Xiang Xiao1,2, Yi-Han Jiang1

  • 1State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China.

Human Brain Mapping
|December 17, 2020
PubMed
Summary
This summary is machine-generated.

This study introduces a novel mathematical framework and algorithm for optimizing functional near-infrared spectroscopy (fNIRS) optode placement using transcranial brain atlases (TBAs). The new method offers more accurate and consistent fNIRS group imaging compared to traditional approaches.

Keywords:
fNIRSfunctional near-infrared spectroscopynavigationoptode arrangementoptode montage designoptode placementtopographytranscranial brain atlas

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Area of Science:

  • Neuroimaging
  • Biomedical Engineering
  • Cognitive Neuroscience

Background:

  • Accurate optode arrangement is vital for functional near-infrared spectroscopy (fNIRS) group studies.
  • Transcranial brain atlases (TBAs) have been used manually for optode guidance, but lack a clear theoretical basis, leading to subjective application.
  • Individual structural MRI data is often unavailable, necessitating alternative methods for precise optode placement.

Purpose of the Study:

  • To establish a theoretical foundation for TBA-based optode arrangement optimization using a mathematical framework.
  • To develop and validate an algorithm for automated optode arrangement on a virtual scalp.
  • To compare the proposed method's performance against the standard 10/20 system for fNIRS group imaging.

Main Methods:

  • Developed a mathematical framework to define the theoretical basis for TBA-guided optode arrangement.
  • Created an algorithm for automatic optode placement on a virtual scalp.
  • Utilized a portable navigation system to transfer the virtual montage to participants' heads and compared with the 10/20 system using finger-tapping and working memory tasks.

Main Results:

  • The proposed TBA-based algorithm demonstrated superior performance in optode montage design and scalp placement accuracy compared to the 10/20 system.
  • fNIRS brain activation analysis showed more accurate and consistent results with the new method.
  • Ground truth indices derived from individual MRI data supported the enhanced accuracy and efficiency of the TBA-guided approach.

Conclusions:

  • The developed mathematical framework and algorithm provide a robust, objective, and efficient method for optode arrangement in fNIRS group studies.
  • This approach significantly improves the accuracy and consistency of fNIRS neuroimaging, especially when individual MRI data is unavailable.
  • The findings suggest a paradigm shift from subjective to data-driven optode placement for enhanced reliability in cognitive neuroscience research.