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Updated: Jul 28, 2026

Assessing the Secretory Capacity of Pancreatic Acinar Cells
Published on: August 28, 2014
New suggestions for the physiological role of secretory protein-I
S U Gorr1, R Kumarasamy, W L Dean
1Department of Oral Biology, University of Louisville, KY 40292.
Abstract:
A major endocrine secretory protein of unknown function termed secretory protein-I or, alternatively, chromogranin A, is attracting increasing attention. Because of its abundance and apparently universal presence in endocrine and neuroendocrine cells, many suggestions for a physiological role have been advanced. Recent data provide the first firm bases for some proposed functions that include a regulator of a novel protease capable of converting prohormones to hormones, a hormone precursor, and through its calcium-binding and aggregating properties, a secretory granule condensing protein.
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