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Marine Compounds and Cancer: Updates 2020.
Sergey A Dyshlovoy1,2,3, Friedemann Honecker2,4
1Laboratory of Pharmacology, A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, 690041 Vladivostok, Russia.
Marine Drugs
|December 18, 2020
Summary
Marine-derived anticancer drugs are rapidly expanding, with nine approved by 2020. This growth highlights the ocean as a vital source for novel cancer therapies.
Area of Science:
- Marine Biotechnology
- Pharmacology
- Drug Discovery
Background:
- The ocean represents a largely untapped reservoir for novel therapeutic compounds.
- Marine natural products have yielded a growing number of clinically relevant anticancer agents.
Discussion:
- The increasing number of marine-derived anticancer drugs signifies a successful translation from natural product research to clinical application.
- Challenges in marine drug discovery include sustainable sourcing, complex compound isolation, and scalable synthesis.
Key Insights:
- Nine marine-derived anticancer drugs were on the market by the end of 2020.
- The field of marine anticancer drug development is experiencing exponential growth.
Outlook:
- Continued exploration of marine biodiversity is expected to yield further anticancer drug candidates.
- Advancements in synthetic biology and high-throughput screening will accelerate the development of marine-based cancer treatments.
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