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Related Experiment Videos

Thermedics' approach to ventricular support systems.

M Szycher1, W Clay, D Gernes

  • 1Thermedics, Inc., Woburn, MA 01888-1799.

Journal of Biomaterials Applications
|July 1, 1986
PubMed
Summary
This summary is machine-generated.

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Temporary and permanent ventricular assist systems (VAS) can support weakened hearts. These devices, including left ventricular assist devices (LVADs), utilize advanced materials and energy transmission for improved biocompatibility and reduced infection risk.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Surgery
  • Materials Science

Background:

  • Weakened heart tissue may recover if temporarily supported by a left ventricular assist device (LVAD).
  • Existing ventricular assist systems (VAS) require ongoing development for improved efficacy and safety.

Purpose of the Study:

  • To describe temporary and permanent ventricular assist systems developed by Thermedics, Inc.
  • To present clinical data for temporary LVADs and discuss the technology for permanent VAS.
  • To analyze materials and designs for enhanced biocompatibility and performance.

Main Methods:

  • Clinical data analysis of pneumatically driven temporary LVADs.
  • Description of subsystems for a permanent VAS, including a low-speed, torque-motor driven blood pump.

Related Experiment Videos

  • Evaluation of transcutaneous energy transmission and biocompatible polyurethanes.
  • Analysis of sintered metal powders and a lenticular pump design.

    • Main Results:

    • A case report details LVAD implantation followed by heart transplant.
    • Transcutaneous energy transmission eliminates infection risk associated with percutaneous methods.
    • Flocked polyurethane surfaces promote antithrombogenic biological lining growth.
    • Sintered metal powders are efficient for rigid pump components; lenticular design addresses pressure differentials.

    Conclusions:

    • Ventricular assist devices offer a viable option for supporting patients with heart conditions.
    • Technological advancements in materials and energy transmission enhance the safety and efficacy of VAS.
    • The development of permanent VAS is progressing towards preclinical trials, with a focus on biocompatibility and pump design.