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Visual Loss after Platelet-rich Plasma Injection into the Face
Emely Z Karam1,2, Alexander Gan2, Rafael Muci Mendoza3,4
1Neuro-ophthalmology Department, Centro Medico Docente la Trinidad, Caracas, Venezuela.
Neuro-Ophthalmology (Aeolus Press)
|December 18, 2020
Summary
Platelet-rich plasma (PRP) injections for cosmetic facial fillers can cause blindness. Iatrogenic occlusion of the ophthalmic artery following PRP treatment led to irreversible vision loss in four patients.
Area of Science:
- Ophthalmology
- Dermatology
- Regenerative Medicine
Background:
- Platelet-rich plasma (PRP) is a popular cosmetic filler for facial rejuvenation.
- Cosmetologists commonly administer PRP injections for aesthetic purposes.
Observation:
- Four patients developed irreversible blindness after receiving PRP injections in the glabellar or nasolabial areas.
- Ophthalmic artery occlusion was diagnosed immediately following injections.
- Funduscopic examination revealed central retinal artery and choroidal occlusions.
Findings:
- All patients experienced vision loss attributed to iatrogenic occlusion of the ophthalmic artery.
- Skin scarring presented similar characteristics across all affected patients.
- Long-term complications included retinal pigment dispersion and optic disc abnormalities.
Implications:
- This study highlights a severe risk associated with cosmetic PRP injections.
- Recognizing characteristic skin scarring may aid in diagnosing PRP-related complications.
- Ophthalmologists and dermatologists should be aware of these potential adverse events.
