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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
162
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

176
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
176
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

649
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Related Experiment Video

Updated: Nov 25, 2025

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
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COVID-19 Mortality in Transplant Recipients.

M Alfishawy1,2, A Elbendary3, M Mohamed4

  • 1Infectious Diseases Consultants and Academic Researchers of Egypt (IDCARE), Cairo, Egypt.

International Journal of Organ Transplantation Medicine
|December 18, 2020
PubMed
Summary
This summary is machine-generated.

Organ transplant recipients face high mortality from COVID-19, with a 20% death rate observed in this study. Outcomes varied by country and were worse in older patients with comorbidities.

Keywords:
COVID-19Heart transplantKidney transplantLiver transplantTransplant recipients

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Area of Science:

  • Transplant medicine
  • Infectious diseases
  • Public health

Background:

  • Organ transplant recipients are immunocompromised and highly susceptible to infections.
  • The emergence of SARS-CoV-2 (COVID-19) posed a significant threat to this vulnerable population.
  • Previous data on COVID-19 outcomes in transplant patients were limited.

Purpose of the Study:

  • To assess the mortality rate of COVID-19 in organ transplant recipients.
  • To identify factors associated with mortality in this patient group.

Main Methods:

  • A systematic literature review was performed using PubMed and Google Scholar.
  • Studies published between January 1, 2020, and May 7, 2020, focusing on COVID-19 in transplant recipients were included.
  • Data from 46 articles encompassing 320 transplant patients were analyzed.

Main Results:

  • The overall COVID-19 mortality rate among transplant recipients was 20%.
  • Mortality varied across different organ transplant types (kidney, liver, heart, lung) and geographical regions.
  • Older age, male sex, and pre-existing conditions like hypertension and diabetes were common among deceased patients, with acute respiratory distress syndrome being the most frequent cause of death.

Conclusions:

  • Organ transplant recipients experienced a high mortality rate due to COVID-19.
  • Outcomes were influenced by country-specific outbreak settings and patient comorbidities.
  • Elderly transplant recipients with comorbidities represent a particularly high-risk group for severe COVID-19 outcomes.