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Updated: Nov 25, 2025

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Emphysematous cholecystitis during the treatment of heat stroke
Naomasa Yoshiyama1,2, Hideshi Okada1, Takahito Miyake1
1Department of Emergency and Disaster Medicine Gifu University Graduate School of Medicine Gifu Japan.
Background:
During a heat stroke, microvascular injury may occur as a result of thermal damage and systemic hypoperfusion. We present a case of an older woman who experienced emphysematous cholecystitis during a treatment of heat stroke.
Case Presentation:
A 91-year-old woman presented unconscious with a blood pressure, pulse, and core temperature of 73/48 mmHg, 135 bpm, and 39.8°C, respectively. The patient was diagnosed with heat stroke. Twenty-two hours after arrival, the patient fell into septic shock. We diagnosed emphysematous cholecystitis and performed an emergency cholecystectomy. As the bile culture was positive for Clostridium perfringens, meropenem was administered. The patient was transferred for rehabilitation 32 days after admission.
Conclusions:
Emphysematous cholecystitis can present during a treatment of heat stroke. An abdominal X-ray examination should be performed during treatment of heat stroke in the acute phase regardless of the physical assessment.
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