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Updated: Nov 25, 2025

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
Aspirin-exacerbated respiratory disease: Update on medical management
Andrew A White1, Katharine Woessner1, Ronald Simon1
1Scripps Clinic, Division of Allergy, Asthma and Immunology, Scripps Green Hospital, San Diego, CA, USA.
Abstract:
Aspirin-exacerbated respiratory disease (AERD) is frequently diagnosed in patients with severe type 2 airway inflammation presenting with nasal polyps and severe asthma. It has been associated with a recalcitrant course with high medical and surgical requirements. The advent of recent biological and other targeted treatments show promise in the medical management of patient with AERD. The goal of complete disease control where patients no longer require recurrent surgical procedures, systemic corticosteroid exposure and may live with a stable and relatively normal quality of life is now within reach. Further work is necessary to identify biomarkers predictive of treatment response.
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