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Related Experiment Video

Updated: Nov 25, 2025

A Model of Free Tissue Transfer: The Rat Epigastric Free Flap

A Model of Free Tissue Transfer: The Rat Epigastric Free Flap

Published on: January 15, 2017

"Pingpong racket" flap model for evaluating flap survival.

Lijun Wu¹, Suyue Gao¹, Kai Tian¹

¹Department of Plastic and Aesthetic Surgery, the Second Affiliated Hospital of Soochow University, Suzhou, China.

Journal of Cosmetic Dermatology

|December 18, 2020

Summary

A novel "pingpong racket" rat flap model simplifies evaluating treatments for random skin flap survival. This model effectively assesses drug and biomaterial efficacy without needing to detect blood vessels, improving research efficiency.

Keywords:

random flap rat model slender narrow pedicle flap

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Area of Science:

Regenerative Medicine
Surgical Innovation
Biomaterials Science

Background:

Random skin flaps are crucial for tissue repair but suffer from poor survival due to limited vascularity.
Existing methods for evaluating flap survival promotion are challenging.
A new model is needed to reliably assess therapeutic interventions for random skin flaps.

Purpose of the Study:

To develop and validate a novel rat dorsal flap model for evaluating treatments aimed at improving random skin flap survival.
To establish a reliable and reproducible method for assessing the efficacy of drugs and biomaterials in promoting flap survival.

Main Methods:

A
pingpong racket
shaped dorsal flap with adjustable pedicle length was created in rats.
Flap survival was quantified using digital photography and computer-assisted analysis.
The model was designed to avoid the need for pre-detected blood vessel procedures.

Main Results:

A reproducible flap model with a 1 cm pedicle width and 3 cm flap diameter was established.
Necrosis ratios varied significantly with pedicle length: 29.88% (2 cm), 74.69% (3 cm), and 95.52% (4 cm).
The model demonstrated sensitivity to pedicle length, indicating its utility for evaluating interventions.

Conclusions:

The 3 cm pedicle length flap is optimal for evaluating drugs that promote skin flap survival.
The rat dorsal "pingpong racket" flap model is easy to handle, avoids vessel detection, and yields reliable results.
This model offers a valuable tool for preclinical assessment of flap survival-enhancing therapies.