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Updated: Nov 25, 2025

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3D Printing of Biocompatible Shape-Memory Double Network Hydrogels.

Jiehao Chen1, Jiahe Huang2, Yuhang Hu1,2

  • 1The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.

ACS Applied Materials & Interfaces
|December 18, 2020
PubMed
Summary

This study introduces a novel 3D-printable shape-memory double network (DN) hydrogel using polyacrylamide and gelatin. This breakthrough offers enhanced toughness and shape-fixing capabilities for advanced biomedical applications.

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Additive Manufacturing

Background:

  • Shape-memory hydrogels offer versatile biomedical applications due to their tunable properties.
  • Traditional shape-memory hydrogels exhibit brittleness, limiting their mechanical performance.
  • Double network (DN) hydrogels enhance mechanical properties but 3D printable shape-memory DN hydrogels remain elusive.

Purpose of the Study:

  • To develop a 3D printable, biocompatible shape-memory double network (DN) hydrogel.
  • To investigate the potential of combining polyacrylamide and gelatin networks for shape-memory functionality.
  • To overcome the limitations of brittleness in conventional shape-memory hydrogels.

Main Methods:

  • A one-pot fused deposition method was employed for 3D printing.
Keywords:
biocompatibledouble networkhydrogelsshape memorytough

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  • The hydrogel ink comprised polyacrylamide (PAAm) for permanent shape and gelatin for temporary shape fixation.
  • Ink composition was optimized for printing quality and shape-memory performance.

    • Main Results:

    • The developed DN hydrogel demonstrated 3 to 7 times higher fracture toughness compared to single-network hydrogels.
    • The material exhibited robust shape fixation, capable of 300% elongation and 10% compression.
    • Successful 3D printing of a biocompatible shape-memory DN hydrogel was achieved.

    Conclusions:

    • The 3D-printed shape-memory DN hydrogel offers superior mechanical integrity and shape transformation capabilities.
    • This innovation paves the way for advanced applications in medical robots and self-deployable devices.
    • The study presents a significant advancement in the field of functional hydrogel materials.