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Updated: Nov 25, 2025
Analysis of Combinatorial miRNA Treatments to Regulate Cell Cycle and Angiogenesis
Published on: March 30, 2019
MiR-155 affects proliferation and apoptosis of bladder cancer cells by regulating GSK-3β/β-catenin pathway
1Department of Urology, Key Laboratory of Gansu Province for Urological Diseases, Department of Urology of Lanzhou University Second Hospital, Urology institute of Lanzhou University Second Hospital, Lanzhou, Gansu, P.R. China.
Abstract:
Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "MiR-155 affects proliferation and apoptosis of bladder cancer cells by regulating GSK-3β/β-catenin pathway, by Z.-C. Dong, D. Zhang, X.-X. Zhang, Z.-Q. Yao, H. Wu, C.-H. Chen, J.-Q. Tian, published in Eur Rev Med Pharmacol Sci 2019; 23 (13): 5682-5690-DOI: 10.26355/eurrev_201907_18305-PMID: 31298320" has been withdrawn. The Publisher apologizes for any inconvenience this may cause. https://www.europeanreview.org/article/18305.
Insights
This article on miR-155, bladder cancer cell proliferation, and apoptosis has been withdrawn due to suspected research misconduct. The publisher retracted the study after authors failed to verify data originality.
Area of Science:
- Oncology
- Molecular Biology
- Pharmacology
Background:
- The study investigated the role of microRNA-155 (miR-155) in bladder cancer.
- It aimed to understand how miR-155 influences cancer cell proliferation and apoptosis.
- The research focused on the regulatory pathway involving GSK-3β and β-catenin.
Purpose of the Study:
- To elucidate the mechanism by which miR-155 affects bladder cancer cell behavior.
- To determine the involvement of the GSK-3β/β-catenin signaling pathway in miR-155's action.
Main Methods:
- The study involved experiments on bladder cancer cells.
- It likely utilized molecular biology techniques to assess miR-155 expression and its downstream effects.
- Analysis of the GSK-3β/β-catenin pathway was a key component.
Main Results:
- The original study reported that miR-155 affects proliferation and apoptosis in bladder cancer cells.
- Findings suggested that miR-155 regulates the GSK-3β/β-catenin pathway.
Conclusions:
- The article has been withdrawn due to suspected research misconduct.
- Authors did not respond to requests to prove the originality of data and figures.
- The publisher retracted the publication.
