A New Device for Autologous Small Volume Fat Grafting

Area of Science:

• Regenerative Medicine
• Plastic Surgery
• Biotechnology

Background:

• Existing fat grafting techniques often involve cumbersome processing to isolate adipose tissue.
• Improving the efficiency and consistency of fat processing is crucial for clinical applications.

Purpose of the Study:

• To compare the fat processing efficiency of the novel Push-to-Spin (P2S) system with common methods.
• To validate the quality of adipose tissue after processing with the P2S system.

Main Methods:

• Human lipoaspirate samples were processed using the P2S system, cotton gauze (Telfa) rolling, or centrifugation (Coleman technique).
• Processing efficiency was assessed by time, fat harvest ratio, and fat processed ratio.
• Tissue morphology and adipocyte viability were evaluated via histology and immunohistochemistry.

Main Results:

• The P2S system significantly reduced processing time compared to other methods.
• All tested methods yielded comparable fat harvest and processing ratios.
• Adipose grafts processed with P2S, Telfa, and Coleman techniques showed similar cellularity and adipocyte viability markers.

Conclusions:

• The P2S device provides an efficient, user-friendly, and potentially cost-effective solution for fat processing in various settings.
• Adipocyte quality, morphology, and viability are maintained with the P2S system.
• This technology streamlines fat grafting procedures, enhancing surgeon efficiency and patient outcomes.