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[Non-tuberculous infections of the spine]
J L Beguiristáin1, C Villas, A Garbayo
1Dpto. de Cirugía Ortopédica y Traumatología, Universitaria Facultad de Medicina, Universidad de Navarra, Pamplona.
Abstract:
Non tuberculous spondylodiscitis of the rachis is an uncommon entity that affects boys and male adults with greater frequency. The zone with higher incidence of affection is the lumbar region. Usually the causal germ travels through the hematogenous via from an extrarachidial infectious area. Clinical manifestations begin with an acute segmentary rachialgia and paravertebral muscular contracture while presenting fever. In special cases of little boys or when having radiated pain, the presenting form could be confusing. There is always a vertebral rigidity when performing the physical exam and an increase of the globular sedimentation rate. A septic leukocytal formula is not always present. Between the onset of symptoms and the appearance of radiologic alterations (decrease in the height of the disc, erosion and vertebral destruction, reactive bone neo-formation) there is a variable two to eight weeks latency period. Scintigraphy with Tc99 and Ga67 and CAT scan are very important when facing definite diagnosis. To be able to reach a bacteriological diagnosis, we employ puncture-aspiration of the disc. The isolated germ in most cases is staphylococcus aureus. The most complex differential diagnosis is with tuberculous spondylodiscitis. The evolution is favorable if the treatment is initiated early and if it is adequate (antibiotic therapy and immobilization). If this is not done, recurrences and chronicity of the infection can occur, as well as orthopaedic (Kyphosis) and neurological complications.
Insights
Non-tuberculous spondylodiscitis, often affecting the lumbar spine in males, presents with back pain and fever. Early antibiotic treatment and immobilization are crucial for favorable outcomes and preventing complications.
Area of Science:
- Orthopedics
- Infectious Diseases
- Radiology
Context:
- Non-tuberculous spondylodiscitis is an uncommon spinal infection.
- It predominantly affects male children and adults, with the lumbar region being the most common site.
- Hematogenous spread from extrarachidial infections is the usual transmission route.
Purpose:
- To outline the clinical presentation, diagnostic challenges, and management of non-tuberculous spondylodiscitis.
- To differentiate it from tuberculous spondylodiscitis.
- To emphasize the importance of early diagnosis and treatment.
Summary:
- Clinical signs include acute spinal pain, paravertebral muscle contracture, fever, and vertebral rigidity.
- Radiographic changes appear after a 2-8 week latency period, including disc height loss and vertebral destruction.
- Staphylococcus aureus is the most common causative agent; diagnosis is aided by imaging (CT, scintigraphy) and disc aspiration.
Impact:
- Prompt and adequate treatment (antibiotics, immobilization) leads to favorable outcomes.
- Delayed or inadequate treatment can result in recurrences, chronic infection, kyphosis, and neurological deficits.
- Understanding these aspects is vital for effective patient management and preventing long-term sequelae.