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Related Experiment Video

Updated: Nov 25, 2025

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems
06:45

Development of a Benchtop Model for Evaluating the Compatibility of Wound Dressing Materials with Negative Pressure Wound Therapy Systems

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Early physiotherapy experience with a biodegradable polyurethane dermal substitute: Therapy guidelines for use.

Brads Schmitt1, Kathryn Heath2, Rochelle Kurmis2

  • 1Adult Burns Service, Physiotherapy Department, RAH, Australia; Adult Burns Service, RAH, Australia.

Burns : Journal of the International Society for Burn Injuries
|December 19, 2020
PubMed
Summary

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Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis: a synopsis of MS-STAT2, a multicentre, randomised controlled, double-blind, phase 3 clinical trial.

Health technology assessment (Winchester, England)·2026
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A case series to evaluate burn therapy practices after application of Biodegradable Temporising Matrix (BTM).

Scars, burns & healing·2026
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Computed tomography assessment after out-of-hospital cardiac arrest resuscitation.

Resuscitation plus·2026
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Differentiating scar behaviour: Transepidermal water loss in delayed healing and skin graft scars.

Burns : journal of the International Society for Burn Injuries·2026
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Response to letter re: "Commonly recommended moisturizing products effect on transepidermal water loss and hydration in a scar model".

Burns : journal of the International Society for Burn Injuries·2026
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Choosing the Right Tewl Device: A Comparison of Inter- and Intra-Device Reliability of the Vapometer and Dermalab across Measurement Ranges.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2026

This study developed range of motion (ROM) guidelines for adult burn patients treated with a synthetic dermal substitute. Early mobilization and improved joint ROM were observed as clinicians gained experience, leading to good functional and cosmetic outcomes.

Area of Science:

  • Regenerative Medicine
  • Burn Care
  • Physical Therapy

Background:

  • Adult burn centers increasingly utilize advanced wound care technologies.
  • Synthetic dermal substitutes offer potential benefits in managing complex burn injuries.
  • Establishing optimal rehabilitation protocols is crucial for maximizing functional recovery after burn treatment.

Purpose of the Study:

  • To investigate and develop range of motion (ROM) and mobilization guidelines for adult burn patients treated with a novel synthetic dermal substitute.
  • To assess the impact of the synthetic dermal substitute on the timing of ROM commencement and mobilization clearance.
  • To evaluate joint ROM and scar outcomes following the application of the synthetic dermal substitute.

Main Methods:

  • Retrospective audit of the first 20 adult burn patients receiving the synthetic dermal substitute.
Keywords:
AmbulationArtificialBurnsCicatrixHypertrophicPhysical therapy modalitiesRange of motionSkin

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  • Data collection included days to ROM commencement, mobilization clearance, and joint ROM (elbow, knee, shoulder) before and after split-skin grafting (SSG).
  • Scar assessments were performed at 12 months post-injury using validated scar assessment scales.

    • Main Results:

    • Mobilization clearance occurred at a mean of 10.4 days post-substitute application (lower limbs).
    • Active ROM commenced at a mean of 9.9 days (upper limbs) and 12.7 days (lower limbs) post-substitute application.
    • Significant improvements in joint flexion (knee, elbow, shoulder) were noted post-SSG, approaching normal values, with maintained elbow extension and no knee extension contractures; scar assessments indicated good cosmetic results.

    Conclusions:

    • A learning curve exists for therapists managing patients with this synthetic dermal substitute, with earlier active therapy progression observed as experience increased.
    • Guidelines for therapy treatment have been developed and will be continuously evaluated and refined.
    • The synthetic dermal substitute, coupled with evolving therapy protocols, facilitates positive functional and cosmetic recovery in adult burn patients.