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Updated: Sep 27, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Acquired paroxysmal movement disorders
1Department of Neurology, University of Wisconsin Hospital, Madison 53792.
Insights
Acquired paroxysmal movement disorders, often following childhood encephalopathy, are distinct from familial types. Antiepileptic drugs may improve symptoms in affected children.
Area of Science:
- Neurology
- Pediatric Neurology
- Movement Disorders
Background:
- Familial paroxysmal dyskinesias are more commonly reported than acquired forms.
- Acquired paroxysmal movement disorders are rare and often associated with specific neurological events.
Observation:
- This study describes three children with acquired paroxysmal movement disorders following early childhood encephalopathy.
- These cases align with three previously reported similar cases, suggesting a pattern.
Findings:
- Movement disorders developing after perinatal encephalopathy represent a distinct clinical entity.
- Initiation of antiepileptic medications led to clinical improvement in these patients.
Implications:
- Recognizing movement disorders post-encephalopathy as a distinct entity is crucial for diagnosis.
- Antiepileptic drug therapy shows promise for managing these acquired movement disorders in children.
Abstract:
Acquired paroxysmal movement disorders are reported less frequently than the familial forms of paroxysmal dyskinesias. Three children, with the acquired form of the disorder which followed an early childhood encephalopathic event, are described. Three similarly affected children have been reported previously. Movement disorders developing after perinatal encephalopathy appear to be a distinct entity. Patients with this condition demonstrated clinical improvement following the initiation of antiepileptic medications.
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