Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

77.5K
Overview
77.5K
Transgenic Organisms00:53

Transgenic Organisms

32.6K
Overview
32.6K
Transgenic Plants02:50

Transgenic Plants

8.1K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
8.1K
Plant Breeding and Biotechnology01:59

Plant Breeding and Biotechnology

20.6K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
20.6K
In-vitro Mutagenesis01:16

In-vitro Mutagenesis

15.7K
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
15.7K
CRISPR01:59

CRISPR

55.3K
Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
55.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Considerations on the risk assessment of genetically modified plants containing transformation events stacked by conventional crossing.

EFSA journal. European Food Safety Authority·2026
Same author

Assessment of genetically modified soybean FG72 for renewal authorisation under Regulation (EC) No 1829/2003 (dossier GMFF-2025-33580).

EFSA journal. European Food Safety Authority·2026
Same author

WIP transcriptional regulators modulate developmental progression in both life cycle phases of a moss.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Risk assessment of new sequencing information on GM maize event DAS-59122-7.

EFSA journal. European Food Safety Authority·2026
Same author

Scientific Opinion on an application by Dow AgroSciences (EFSA-GMO-NL-2013-116) for placing on the market of genetically modified insect-resistant soybean DAS-81419-2 for food and feed uses, import and processing under Regulation (EC) No 1829/2003.

EFSA journal. European Food Safety Authority·2026
Same author

Scientific Opinion on an application by DOW AgroSciences LLC (EFSA-GMO-NL-2010-89) for placing on the market the genetically modified herbicide-tolerant maize DAS-40278-9 for food and feed uses, import and processing under Regulation (EC) No 1829/2003.

EFSA journal. European Food Safety Authority·2026

Related Experiment Video

Updated: Nov 25, 2025

Preventing the Spread of Malaria and Dengue Fever Using Genetically Modified Mosquitoes
17:50

Preventing the Spread of Malaria and Dengue Fever Using Genetically Modified Mosquitoes

Published on: July 4, 2007

12.8K

Gene Drive-Modified Organisms: Developing Practical Risk Assessment Guidance.

Yann Devos1, Michael B Bonsall2, Leslie G Firbank3

  • 1GMO Unit, European Food Safety Authority (EFSA), Parma, Italy.

Trends in Biotechnology
|December 21, 2020
PubMed
Summary

Stakeholders need better risk assessment guidance for releasing gene drive-modified organisms into the environment. This paper offers recommendations for creating practical guidance documents.

Keywords:
engineered gene drivesmodellingmonitoringprecautionary principleproblem formulationsynthetic biology

More Related Videos

Small-Cage Laboratory Trials of Genetically-Engineered Anopheline Mosquitoes
07:45

Small-Cage Laboratory Trials of Genetically-Engineered Anopheline Mosquitoes

Published on: May 1, 2021

3.0K
Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes
09:41

Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes

Published on: September 15, 2023

1.1K

Related Experiment Videos

Last Updated: Nov 25, 2025

Preventing the Spread of Malaria and Dengue Fever Using Genetically Modified Mosquitoes
17:50

Preventing the Spread of Malaria and Dengue Fever Using Genetically Modified Mosquitoes

Published on: July 4, 2007

12.8K
Small-Cage Laboratory Trials of Genetically-Engineered Anopheline Mosquitoes
07:45

Small-Cage Laboratory Trials of Genetically-Engineered Anopheline Mosquitoes

Published on: May 1, 2021

3.0K
Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes
09:41

Quantifying Fitness Costs in Transgenic Aedes aegypti Mosquitoes

Published on: September 15, 2023

1.1K

Area of Science:

  • Environmental Science
  • Risk Assessment
  • Genetic Engineering

Background:

  • Gene drive-modified organisms (GMOs) present unique challenges for environmental risk assessment.
  • There is a recognized need for updated and practical guidance for assessing risks associated with their deliberate release.

Purpose of the Study:

  • To address the need for improved risk assessment guidance for gene drive-modified organisms.
  • To provide recommendations for developing practical and useful guidance based on drafting experience.

Main Methods:

  • Review of existing risk assessment frameworks.
  • Analysis of challenges encountered in drafting guidance for gene drive technologies.
  • Synthesis of recommendations for future guidance development.

Main Results:

  • Identification of key challenges in creating effective risk assessment guidance for gene drive GMOs.
  • Development of actionable recommendations for stakeholders involved in guidance preparation.

Conclusions:

  • Practical and effective risk assessment guidance for gene drive GMOs is achievable.
  • Collaboration and experience-based insights are crucial for successful guidance development.