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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

305
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
305

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Related Experiment Video

Updated: Nov 25, 2025

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
05:45

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5

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Modified Duhamel's Two-Staged Procedure for Hirschsprung's Disease: Further Modifications for Improved Outcomes.

Nitin James Peters1, Prema Menon1, K L N Rao1

  • 1Department of Pediatric Surgery, PGIMER, Chandigarh, India.

Journal of Indian Association of Pediatric Surgeons
|December 21, 2020
PubMed
Summary

The modified Duhamel

Keywords:
Colostomycontrast enemahirschsprung's diseasemodified Duhamel procedureoutcome analysisquality of life

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Area of Science:

  • Pediatric Surgery
  • Gastroenterology

Background:

  • Hirschsprung's disease requires surgical intervention.
  • The modified Duhamel's procedure is a two-staged approach for treatment.

Purpose of the Study:

  • To evaluate short- and long-term outcomes.
  • To assess quality of life (QOL) after the modified Duhamel's procedure for Hirschsprung's disease.

Main Methods:

  • Retrospective analysis of patients undergoing the modified Duhamel's procedure.
  • Inclusion criteria: initial Hartmann's procedure, bowel preparation, and low colo-anal anastomosis.
  • Data collected via interview-based questionnaire with a minimum 2-year follow-up.

Main Results:

  • Initial perineal excoriation and soiling reduced significantly within 2 years.
  • Short-term postoperative issues included constipation and altered stool consistency.
  • Long-term results showed excellent fecal continence (97.1%) and good QOL (95.4%).

Conclusions:

  • Short-term bowel dysfunction and soiling improve significantly over time.
  • The modified Duhamel's procedure leads to good long-term outcomes and quality of life in Hirschsprung's disease patients.