Related Experiment Video
Updated: Jan 6, 2026

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
Published on: August 25, 2021
Gene therapy
A Drugan1, O J Miller, M I Evans
1Department of Obstetrics and Gynecology, Hutzel Hospital/Wayne State University, Detroit, Mich.
Abstract:
Severe genetic disorders are potentially correctable by the addition of a normal gene into tissues. Although the technical problems involving integration, stable expression, and insertional damage to the treated cell are not yet fully solved, enough scientific progress has already been made to consider somatic cell gene therapy acceptable from both the ethical and scientific viewpoints. The resolutions to problems evolving from somatic cell gene therapy will help to overcome the technical difficulties encountered presently with germ line gene manipulation. This procedure would then become morally permissible as it will cause, in time, a reduction in the pool of abnormal genes in the population. Enhancement genetic engineering is technically feasible but morally unacceptable. Eugenic genetic engineering is not technically possible or ethically permissible in the foreseeable future.
Related Concept Videos
Microorganisms in Medicine and Therapeutics
Gene Therapy
What is Genetic Engineering?
Targeted Cancer Therapies
There are several types of targeted therapies against...
In-vitro Mutagenesis
Methods of Nuclear Reprogramming

