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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

262
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
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Updated: Nov 25, 2025

A Mouse Model of Intestinal Partial Obstruction
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Published on: March 5, 2018

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Latest developments in chronic intestinal pseudo-obstruction.

Chang-Zhen Zhu1, Hong-Wei Zhao1, Hong-Wei Lin1

  • 1Department of Gastrointestinal Surgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China.

World Journal of Clinical Cases
|December 21, 2020
PubMed
Summary
This summary is machine-generated.

Chronic intestinal pseudo-obstruction (CIPO) is a rare, heterogeneous condition mimicking bowel obstruction. Early diagnosis and intervention are crucial for improving patient outcomes and quality of life.

Keywords:
Chronic intestinal pseudo-obstructionEnteral nutritionIntestinal obstructionIntestinal transplantationParenteral nutrition

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Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Digestive Diseases

Background:

  • Chronic intestinal pseudo-obstruction (CIPO) presents with symptoms of intestinal obstruction but lacks mechanical blockage.
  • CIPO is characterized by low incidence, non-specific symptoms, and significant heterogeneity, complicating diagnosis.
  • Many patients experience progressive worsening, necessitating interventions and careful nutritional management.

Purpose of the Study:

  • To review the key characteristics of CIPO.
  • To discuss the latest advancements in the diagnosis and treatment of CIPO.
  • To enhance clinician understanding for earlier and more accurate diagnosis and management.

Main Methods:

  • Literature review focusing on CIPO characteristics, diagnostic modalities, and therapeutic strategies.
  • Analysis of current diagnostic tools including imaging and gastrointestinal manometry.
  • Evaluation of treatment options, including nutritional support and small bowel transplantation.

Main Results:

  • CIPO diagnosis is challenging due to its rarity, non-specific symptoms, and heterogeneity.
  • Imaging and gastrointestinal manometry are standard diagnostic approaches.
  • While small bowel transplantation offers a treatment option for advanced cases, long-term prognoses remain suboptimal.

Conclusions:

  • Improved clinician awareness is essential for timely and accurate CIPO diagnosis.
  • Early and appropriate treatment, including nutritional support, can improve patient quality of life.
  • Further research is needed to improve long-term outcomes for CIPO patients.