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[Hypertrophic cardiomyopathy in elderly: causes, diagnostic and treatment approaches]

O S Chumakova1

  • 1Central State Medical Academy of the President of the Russian Federation.

Terapevticheskii Arkhiv
|December 21, 2020
PubMed

Insights

Late-onset hypertrophic cardiomyopathy affects older adults, often diagnosed after age 60. This review explores its causes, diagnosis, and treatment in the elderly population.

Area of Science:

  • Cardiology
  • Genetics
  • Geriatrics

Background:

  • Hypertrophic cardiomyopathy (HCM) is a primary inherited cardiac condition.
  • It presents with significant clinical variability.
  • Approximately 20% of HCM patients receive their initial diagnosis after age 60.

Purpose of the Study:

  • To investigate the factors contributing to the late diagnosis of HCM.
  • To outline current diagnostic strategies for elderly HCM patients.
  • To review therapeutic interventions for HCM in older individuals.

Main Methods:

  • Literature review of studies on late-onset HCM.
  • Analysis of diagnostic criteria and imaging techniques in the elderly.
  • Synthesis of treatment guidelines for geriatric HCM patients.

Main Results:

  • Late-onset HCM may be influenced by genetic modifiers or environmental factors.
  • Diagnostic challenges in the elderly include comorbidities and atypical presentations.
  • Treatment requires careful consideration of age-related physiological changes and pharmacologic risks.

Conclusions:

  • Late diagnosis of HCM in the elderly is a recognized clinical scenario.
  • Tailored diagnostic and therapeutic approaches are essential for older adults with HCM.
  • Further research is needed to optimize management strategies for this demographic.

Keywords:
diagnosticselderlygeneticshypertrophic cardiomyopathytreatment

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