[Diagnostic and prognostic significance of QRS-T angle]
E V Blinova1, T A Sakhnova1, E S Yurasova1
1National Medical Research Center for Cardiology.
Insights
The QRS-T angle, reflecting ventricular electrical activity, is a key indicator of heart health. This review highlights its prognostic value for mortality and cardiovascular diseases, exploring underlying mechanisms and clinical applications.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Diagnostics
Background:
- The QRS-T angle quantifies ventricular depolarization and repolarization consistency.
- Global myocardial electrical heterogeneity is assessed using the QRS-T angle.
- Recent research highlights the prognostic significance of the QRS-T angle for mortality.
Purpose of the Study:
- To review recent studies on the QRS-T angle's relationship with mortality, coronary heart disease, and heart failure.
- To explore potential mechanisms driving increases in the QRS-T angle.
- To examine the diagnostic and prognostic utility of the QRS-T angle.
Main Methods:
- Systematic literature review of studies published in the last five years.
- Analysis of research investigating the QRS-T angle and cardiovascular outcomes.
- Synthesis of data on mechanisms and clinical applications of the QRS-T angle.
Main Results:
- The QRS-T angle demonstrates prognostic value for overall and cardiovascular mortality.
- Associations between the QRS-T angle and coronary heart disease/heart failure are evident.
- The review discusses potential mechanisms and clinical integration of the QRS-T angle.
Conclusions:
- The QRS-T angle is a valuable indicator of myocardial electrical heterogeneity with significant prognostic implications.
- Further research into its mechanisms and clinical application is warranted.
- The QRS-T angle shows promise for integration into diagnostic and prognostic tools for cardiovascular disease.
Abstract:
The angle between theQRSandTvectors reflects the consistency or inconsistency of the processes of de- and repolarization of the ventricles of the heart and is considered one of the indicators of global electrical heterogeneity of myocardium. In recent years, the prognostic value of theQRS-Tangle has been demonstrated in relation to total and cardiovascular mortality, both in the population and in various groups of patients. The mechanisms of this phenomenon are not completely clear. The review analyses studies published over the past five years on the relationship between theQRS-Tangle and mortality, as well as coronary heart disease and heart failure. Possible mechanisms for increasing theQRS-Tangle are discussed. Data are given on the use of theQRS-Tangle in diagnostic and prognostic scales, including in combination with other indicators of global electrical heterogeneity of myocardium.
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