Related Experiment Video
Updated: Nov 24, 2025
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
Published on: April 4, 2025
[Kidney health for everyone everywhere - from prevention to detection and equitable access to care]
P Kam-Tao Li1, G Garcia-Garcia2, S Lui3
1Chinese University of Hong Kong.
Insights
Chronic kidney disease (CKD) is a growing global health threat and a significant financial burden. Implementing primary, secondary, and tertiary prevention strategies is crucial for managing and potentially halting the progression of kidney disease.
Area of Science:
- Nephrology
- Public Health
- Preventive Medicine
Background:
- Chronic kidney disease (CKD) presents a rapidly escalating global health challenge, projected to be the fifth leading cause of lost life years by 2040.
- CKD significantly contributes to healthcare costs, with dialysis and transplantation consuming substantial portions of national budgets.
- Despite its severity, CKD onset and progression are largely preventable through targeted interventions.
Purpose of the Study:
- To outline and analyze implementable measures for advancing CKD prevention globally.
- To emphasize the importance of primary, secondary, and tertiary preventive strategies for kidney health.
- To advocate for increased political will and specific policies to support CKD prevention efforts.
Main Methods:
- Review and analysis of primary, secondary, and tertiary prevention strategies for CKD.
- Examination of risk factor modification, including lifestyle, environmental exposures, and nephrotoxins.
- Assessment of clinical interventions like blood pressure and glycemic control, and management of comorbidities in advanced CKD.
Main Results:
- Primary prevention involves addressing risk factors, structural abnormalities, and environmental exposures.
- Secondary prevention focuses on blood pressure and glycemic control in individuals with existing kidney disease.
- Tertiary prevention in advanced CKD centers on managing comorbidities to delay renal replacement therapy.
Conclusions:
- A comprehensive, multi-level preventive approach is essential for combating the rising burden of CKD.
- Political commitment and specific national policies are urgently needed to enhance CKD awareness, screening, and management.
- Increased awareness among the public, healthcare professionals, and policymakers is critical for successful CKD prevention.
Abstract:
The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of the annual healthcare budget in high-income countries. Crucially, however, the onset and progression of CKD is often preventable. In 2020, the World Kidney Day campaign highlights the importance of preventive interventions be it primary, secondary or tertiary. This complementing article focuses on outlining and analyzing measures that can beimplemented in every country to promote and advance CKD prevention. Primary prevention of kidney disease should focus on the modification of risk factors and addressing structural abnormalities of the kidney and urinary tracts, as well as exposure to environmental risk factors and nephrotoxins. In persons with pre-existing kidney disease, secondary prevention, including blood pressure optimization and glycemic control, should be the main goal of education and clinical interventions. In patients with advanced CKD, management of co-morbidities such as uremia and cardiovascular disease is a highly recommended preventative intervention to avoid or delay dialysis or kidney transplantation. Political efforts are needed to proliferate the preventive approach. While national policies and strategies for non-communicable diseases might be present in a country, specific policies directed toward education and awareness about CKD screening, management and treatment are often lacking. Hence, there is an urgent need to increase the awareness of the importance of preventive measures throughout populations, professionals and policy makers.
Related Concept Videos
01:28Chronic Kidney Disease III: Interprofessional Care
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
01:25Chronic Kidney Disease I: Introduction
01:18Chronic Kidney Disease IV: Nursing Management
01:12Internal Anatomy of the Kidney
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
01:28Kidney Transplant I: Introduction