Related Experiment Video
Updated: Nov 24, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
Structural racism, socio-economic marginalization, and infant mortality.
J Bishop-Royse1, B Lange-Maia2, L Murray3
1Faculty Scholarship Collaborative, DePaul University, Chicago, IL 60614, USA; Center for Community Health Equity, Chicago, IL, USA.
Structural racism, measured by the Index of Concentration at the Extremes (ICE), is independently linked to higher infant mortality rates (IMRs) in Chicago neighborhoods. This association persists after accounting for socioeconomic factors.
Area of Science:
- Public Health
- Sociology
- Health Equity
Background:
- Infant mortality rates (IMRs) reflect community health and are influenced by socioeconomic and racial factors.
- Structural racism and socioeconomic marginalization are hypothesized contributors to IMR disparities.
Purpose of the Study:
- To examine the association between measures of structural racism and socioeconomic marginalization and IMRs in Chicago.
- To determine if the Index of Concentration at the Extremes (ICE) is significantly related to community-level IMRs.
Main Methods:
- Cross-sectional ecological public health study design using data from 2012-2016 in Chicago.
- Calculated ICE for race and income, racialized socioeconomic status, hardship, inadequate prenatal care (PNC), and single-parent households.
- Negative binomial regression analyzed the relationship between ICE measures and IMRs, controlling for other factors.
Main Results:
- Significant associations were found between racial segregation, economic marginalization, and IMRs.
- Community areas with the lowest ICERace (highest concentration of Black residents) had 3.63 times higher IMRs than those with the highest concentration of White residents.
- After full adjustment, only ICERace remained significantly related to IMRs.
Conclusions:
- Structural racism, as indicated by ICERace, is an independent predictor of IMRs in Chicago.
- This relationship holds even when controlling for socioeconomic marginalization, hardship, family structure, and healthcare access.
- Addressing structural determinants of health inequities is crucial for improving birth outcomes.
More Related Videos
Related Concept Videos
Close Relationships and Culture
Bias in Epidemiological Studies
Regression Toward the Mean
Stereotypes, Prejudice, and Discrimination
Stereotype Content Model
Socioemotional Development during Infancy
Primary Temperament Types

