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Updated: Nov 24, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Thrombectomy for Treatment of Acute Stroke in the COVID-19 Pandemic
Panagiotis Papanagiotou1,2, Guillermo Parrilla3, L Creed Pettigrew4
1Department of Diagnostic and Interventional Neuroradiology, Klinikum Bremen-Mitte, Germany, Bremen, Germany.
Insights
This commentary reviews thrombectomy guidelines and experiences for treating large-vessel occlusion (LVO) stroke in COVID-19 patients. It discusses challenges neuro-interventionalists face when performing thrombectomy during the pandemic.
Area of Science:
- Neurology
- Infectious Diseases
- Interventional Radiology
Background:
- The 2019 novel coronavirus disease (COVID-19) pandemic has impacted various medical fields, including stroke care.
- Emerging evidence suggests a potential link between COVID-19 and cerebrovascular events, such as ischemic stroke.
Purpose of the Study:
- To review current guidelines for mechanical thrombectomy in patients with COVID-19 associated large-vessel occlusion (LVO) stroke.
- To survey the reported clinical experience of performing thrombectomy in COVID-19 patients with acute LVO stroke.
- To discuss the unique challenges encountered by neuro-interventionalists during these procedures.
Main Methods:
- Review of recently published guidelines and recommendations.
- Survey of reported case series and observational studies on thrombectomy for LVO stroke in COVID-19 patients.
- Discussion of practical considerations and challenges based on clinical experience.
Main Results:
- Guidelines for thrombectomy in COVID-19 stroke patients have been promulgated, adapting existing protocols.
- Initial experiences suggest thrombectomy can be safely performed in selected COVID-19 patients with LVO stroke.
- Specific challenges include patient isolation, personal protective equipment (PPE) use, and potential for increased bleeding risk.
Conclusions:
- Mechanical thrombectomy remains a critical treatment for acute LVO stroke, even in the context of COVID-19.
- Adherence to modified protocols and careful patient selection are essential for successful outcomes.
- Neuro-interventionalists must be prepared to manage the unique logistical and clinical challenges posed by performing thrombectomy in COVID-19 patients.
Abstract:
This commentary will focus on the role of thrombectomy for the treatment of embolic stroke during the 2019 novel coronavirus disease (COVID-19). We will begin with review of recently promulgated guidelines for use of thrombectomy in COVID-19-associated stroke. We will then survey the reported experience of thrombectomy applied to treatment of large-vessel occlusion (LVO) stroke in COVID-19. We will conclude by discussing unusual challenges confronted by neuro-interventionalists seeking to perform thrombectomy in COVID-19 patients with acute LVO stroke.
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