Thrombectomy for Treatment of Acute Stroke in the COVID-19 Pandemic

Panagiotis Papanagiotou1,2, Guillermo Parrilla3, L Creed Pettigrew4

  • 1Department of Diagnostic and Interventional Neuroradiology, Klinikum Bremen-Mitte, Germany, Bremen, Germany.

Insights

This commentary reviews thrombectomy guidelines and experiences for treating large-vessel occlusion (LVO) stroke in COVID-19 patients. It discusses challenges neuro-interventionalists face when performing thrombectomy during the pandemic.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Interventional Radiology

Background:

  • The 2019 novel coronavirus disease (COVID-19) pandemic has impacted various medical fields, including stroke care.
  • Emerging evidence suggests a potential link between COVID-19 and cerebrovascular events, such as ischemic stroke.

Purpose of the Study:

  • To review current guidelines for mechanical thrombectomy in patients with COVID-19 associated large-vessel occlusion (LVO) stroke.
  • To survey the reported clinical experience of performing thrombectomy in COVID-19 patients with acute LVO stroke.
  • To discuss the unique challenges encountered by neuro-interventionalists during these procedures.

Main Methods:

  • Review of recently published guidelines and recommendations.
  • Survey of reported case series and observational studies on thrombectomy for LVO stroke in COVID-19 patients.
  • Discussion of practical considerations and challenges based on clinical experience.

Main Results:

  • Guidelines for thrombectomy in COVID-19 stroke patients have been promulgated, adapting existing protocols.
  • Initial experiences suggest thrombectomy can be safely performed in selected COVID-19 patients with LVO stroke.
  • Specific challenges include patient isolation, personal protective equipment (PPE) use, and potential for increased bleeding risk.

Conclusions:

  • Mechanical thrombectomy remains a critical treatment for acute LVO stroke, even in the context of COVID-19.
  • Adherence to modified protocols and careful patient selection are essential for successful outcomes.
  • Neuro-interventionalists must be prepared to manage the unique logistical and clinical challenges posed by performing thrombectomy in COVID-19 patients.

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