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Echocardiographic Features of Cardiac Injury Related to COVID-19 and Their Prognostic Value: A Systematic Review

Neda Shafiabadi Hassani1, Abbas Shojaee2, Zeynab Khodaprast3

  • 1Cardiovascular Research Center, 391934Alborz University of Medical Sciences, Karaj, Iran.

Journal of Intensive Care Medicine
|December 22, 2020
PubMed

Insights

Right ventricular abnormalities, including dilatation and dysfunction, are common echocardiographic findings in COVID-19 patients and indicate a poor prognosis, especially in severe disease.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Imaging

Background:

  • Echocardiographic features of cardiac injury in COVID-19 are not well-consolidated.
  • Prognostic value of these echocardiographic findings is scattered in literature.

Purpose of the Study:

  • To investigate echocardiographic features of cardiac injury in COVID-19.
  • To evaluate the prognostic value of these echocardiographic findings.

Main Methods:

  • Systematic literature search of PubMed, Embase, and Google Scholar.
  • Keywords included "echocard*," "cardiac ultrasound," and COVID-19 related terms.
  • Two researchers independently screened 783 retrieved articles, selecting 11 studies.

Main Results:

  • Right ventricular (RV) dilatation (15.0%-48.9%) and dysfunction (3.6%-40%) were more common than left ventricular (LV) dysfunction (5.4%-40.0%).
  • RV abnormalities were significantly associated with severe COVID-19 and mortality.
  • Rates of abnormalities varied across studies.

Conclusions:

  • RV dilatation and dysfunction are prominent echocardiographic findings in symptomatic COVID-19 patients.
  • These RV abnormalities are particularly evident in severe or deteriorating disease.
  • RV dysfunction is a significant poor prognostic factor in COVID-19.
Abstract

Keywords:
COVID-19echocardiographyleft ventricleprognosisright ventricle

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