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Etiology of Severe Acute Respiratory Infections, Bangladesh, 2017

Md R Rahaman, Karen A Alroy, Chris A Van Beneden

    Emerging Infectious Diseases
    |December 22, 2020
    PubMed

    Insights

    A surge in severe acute respiratory infections (SARI) in Bangladesh was linked to the Influenza A(H1N1)pdm09 virus. Vaccination and antiviral treatments may help control future SARI outbreaks.

    Area of Science:

    • Public Health
    • Infectious Diseases
    • Virology

    Background:

    • A significant increase in severe acute respiratory infections (SARI) was observed in Bangladesh in April 2017.
    • Understanding the causative agent of this SARI surge is crucial for effective public health interventions.

    Purpose of the Study:

    • To identify the pathogen responsible for the 2017 SARI epidemic in Bangladesh.
    • To inform potential strategies for managing and preventing future SARI outbreaks.

    Main Methods:

    • Collection of biological specimens from patients diagnosed with SARI and healthy controls.
    • Utilized multipathogen diagnostic tests for comprehensive etiological analysis.

    Main Results:

    • Influenza A(H1N1)pdm09 was identified as the primary virus associated with the SARI epidemic.
    • The findings indicate a specific viral strain driving the observed increase in respiratory illness.

    Conclusions:

    • The Influenza A(H1N1)pdm09 virus played a significant role in the 2017 SARI outbreak in Bangladesh.
    • Recommendations include the implementation of targeted vaccination campaigns and the use of empiric antiviral therapies to mitigate the impact of similar future events.
    Keywords:
    Bangladeshinfluenzarespiratory infectionsseverevaccinevaccine-preventable diseasesviruses

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