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General concepts on hemophilia A and on women carrying the disease

María E Mingot Castellano1

  • 1Hematology and Hemotherapy Department, Hospital Universitario Virgen del Rocio, Sevilla, Spain.

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|December 22, 2020
PubMed

Hemophilia A affects one in every 5000 live male births. As the disorder follows a hereditary X-linked recessive pattern, women who inherit the mutation become carriers of the disease. The exact prevalence of carriers of hemophilia A or B is unknown. A search of the literature identified only one study that provides an approximation. According to its authors, for every 100 male with hemophilia there are 277 potential carriers. We will review through this supplement carrier condition from reproductive to care giver and individual point of view.

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