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Updated: Nov 24, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
Colorectal Cancer Screening Methods and Molecular Markers for Early Detection
Ziwei Wu1,2, You Li1,2, Yibin Zhang1,2
1Department of Medical Laboratory, the Central Hospital of Wuhan, Tongji Medical College, 12443Huazhong University of Science and Technology, Wuhan, China.
Abstract:
Colorectal cancer (CRC) is one of the most common malignant tumors in the digestive tract in humans. The development of colorectal cancer is composed of multiple stages, starting with benign adenomatous polyps in the inner wall of the large intestine and rectum, and then gradually developing. Then it developed into advanced adenomas carcinoma in situ and invasive carcinoma. Represents the distant metastasis of the most advanced development. The purpose of this review is to novel routine screening and diagnostic methods (e.g., Endoscopy and CT colonoscopy, SEPT9 methylation assay, Fecal test) and find reliable molecular markers for early diagnosis of CRC.

