Related Experiment Video
Updated: Nov 24, 2025

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Transfusion practices during the COVID-19 pandemic: An experience from a hematology daycare in India
Jayastu Senapati1, Mukul Aggarwal1, Liji Louis2
1Department of Hematology, AIIMS, New Delhi, 110029, India.
Insights
The COVID-19 pandemic caused a 56% reduction in blood transfusion services for hematology patients. Strategies were implemented to support patients during the lockdown, offering insights for future healthcare challenges.
Area of Science:
- Hematology
- Transfusion Medicine
- Public Health
Background:
- The COVID-19 pandemic significantly disrupted global healthcare delivery.
- Transfusion services are critical for patients with hematological conditions.
Purpose of the Study:
- To analyze the impact of the COVID-19 pandemic and lockdown on transfusion services in a hematology daycare.
- To identify and showcase remedial strategies implemented during this period.
Main Methods:
- Retrospective analysis of transfusion data from April 12, 2020, to June 30, 2020 (lockdown period).
- Comparison of transfusion sessions and blood component usage with the same period in 2019.
- Evaluation of transfusion practices across different lockdown phases.
Main Results:
- A 56% overall reduction in transfusion sessions (588 in 2020 vs. 1336 in 2019).
- Significant decreases in packed red blood cells (PRBC) and platelet-rich plasma transfusions.
- Reduced mean PRBC units transfused per session in 2020 (1.11 vs. 1.99, p<0.001).
Conclusions:
- The COVID-19 pandemic and associated lockdowns led to a detrimental reduction in essential transfusion services for hematology patients.
- Remedial strategies were employed to sustain transfusion support, providing valuable insights for managing future healthcare crises.
Abstract:
The Coronavirus disease-19 (COVID-19) pandemic has in multiple ways affected healthcare delivery to non-COVID patients throughout the world. Adequate transfusion services are fundamental in ongoing therapy of patients with hematological ailments. We present the transfusion services in the hematology daycare under the department of Hematology and supported by the Blood Bank at our institution for the period 12th April 2020-30th June 2020, which saw the stringent lockdown and unlocking Phase I in India, declared in lieu of the pandemic. A 56 % reduction in total transfusion sessions was observed in 2020 (588 sessions given to 176 patients) compared to 1336 sessions in 516 patients over the same period in 2019. The reductions were seen across the different blood components (packed red blood cells [PRBC]: 585 vs. 1840, platelet rich plasma: 372 vs. 1313, single donor platelet 18 vs. 16), with a significant reduction in the mean PRBC transfused per PRBC transfusion session (1.11 vs 1.99, p<0.001) in 2020, compared to 2019. There were however no major differences in the transfusion practices across the different phases of the lockdown. Our study highlights the detrimental reduction in transfusion services due to the COVID-19 pandemic and related lockdown and showcases the remedial strategies taken to maximize transfusion support to patients during this period. Our observations might help to provide insights to adequately combat possible similar adverse situations in the future.
Related Concept Videos
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
Standard Precaution
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hemodialysis II: Procedure and Complications

