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Published on: September 20, 2018
Acinetobacter Baumannii Native Valve Infective Endocarditis: A Case Report
Ismahane Lahmidi1, Darar Charmake2, Noha Elouafi2
1Cardiology, Mohammed I University/Mohammed VI University Hospital, Epidemiological Laboratory of Clinical Research and Public Health, Oujda, MAR.
Insights
Infective endocarditis caused by Acinetobacter baumannii is a rare but severe complication in critically ill patients. This case highlights the high mortality associated with A. baumannii endocarditis, even with aggressive treatment.
Area of Science:
- Infectious Diseases
- Cardiology
Background:
- Infective endocarditis (IE) is a serious infection of the heart valves.
- Acinetobacter baumannii is an opportunistic pathogen increasingly associated with healthcare-associated infections.
- IE caused by A. baumannii is rare but carries a high mortality rate, particularly in critically ill patients.
Observation:
- A 54-year-old woman developed A. baumannii infective endocarditis three days after ICU admission.
- Diagnosis was confirmed by positive blood cultures and transthoracic echocardiography showing mitral valve vegetation.
- Despite intensive treatment, the patient's outcome was poor.
Findings:
- Acinetobacter baumannii endocarditis is associated with a higher mortality than HACEK group endocarditis.
- A. baumannii infections in hospitalized patients lead to prolonged hospital stays, increased morbidity, and mortality.
- Aggressive therapeutic regimens may not be sufficient to overcome the severity of A. baumannii IE.
Implications:
- This case underscores the critical need for vigilance in diagnosing and managing A. baumannii infections, especially IE.
- Early recognition and effective antimicrobial strategies are crucial for improving outcomes in A. baumannii endocarditis.
- Further research into optimal treatment protocols for A. baumannii IE is warranted to reduce associated mortality and healthcare costs.
Abstract:
Infective endocarditis caused by Acinetobacter (A.) baumannii is a rare but severe complication that affects seriously ill, hospitalized patients undergoing invasive procedures. It is associated with an increased mortality rate than that of endocarditis due to the HACEK group (Haemophilus species, Aggregatibacter actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, Kingella kingae) gram-negative bacteria. We report a case of a 54-year-old woman who was diagnosed with infective endocarditis caused by A. baumannii three days following her admission to the intensive unit care (ICU). The diagnosis was made on the basis of repeated blood cultures and transthoracic echocardiography, which revealed mobile vegetation attached to the mitral valve. In spite of aggressive therapeutic regimens, outcomes were poor and the patient died. This report underlines the severe nature of A. baumannii infections, which are still associated with a prolonged hospital stay, and increased morbidity, mortality, and medical costs.
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