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Decrease in Enteroviral Meningitis: An Unexpected Benefit of Coronavirus Disease 2019 (COVID-19) Mitigation?

Kami D Kies1, Amber S Thomas1, Matthew J Binnicker1

  • 1Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|December 23, 2020
PubMed

Insights

Enteroviral meningitis typically peaks in the fall. However, the 2020 fall season saw no enteroviral meningitis peak, possibly due to COVID-19 public health measures.

Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Virology

Background:

  • Enteroviral meningitis commonly presents with a seasonal increase in cases during late summer and early autumn.
  • This seasonal pattern is well-documented in clinical microbiology data.

Purpose of the Study:

  • To investigate the deviation from the typical seasonal pattern of enteroviral meningitis in 2020.
  • To explore potential contributing factors for the observed change in prevalence.

Main Methods:

  • Analysis of clinical microbiology laboratory testing data from cerebrospinal fluid samples.
  • Comparison of enteroviral meningitis incidence during the typical peak season (August/September/October) in 2020 versus historical data.

Main Results:

  • The anticipated peak in enteroviral meningitis cases for August, September, and October did not materialize in 2020.
  • This represents a significant departure from the established seasonal trend.

Conclusions:

  • The absence of the typical enteroviral meningitis seasonal peak in 2020 is notable.
  • Coronavirus disease 2019 (COVID-19) mitigation strategies may have influenced this epidemiological shift.
Keywords:
COVID-19PCRenterovirusmeningitis

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