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Updated: Nov 24, 2025

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

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Published on: July 24, 2016

Decrease in Enteroviral Meningitis: An Unexpected Benefit of Coronavirus Disease 2019 (COVID-19) Mitigation?

Kami D Kies¹, Amber S Thomas¹, Matthew J Binnicker¹

¹Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America

|December 23, 2020

Summary

This summary is machine-generated.

Enteroviral meningitis typically peaks in the fall. However, the 2020 fall season saw no enteroviral meningitis peak, possibly due to COVID-19 public health measures.

Keywords:

COVID-19 PCR enterovirus meningitis

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Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds

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Published on: October 29, 2015

Area of Science:

Epidemiology
Infectious Diseases
Virology

Background:

Enteroviral meningitis commonly presents with a seasonal increase in cases during late summer and early autumn.
This seasonal pattern is well-documented in clinical microbiology data.

Purpose of the Study:

To investigate the deviation from the typical seasonal pattern of enteroviral meningitis in 2020.
To explore potential contributing factors for the observed change in prevalence.

Main Methods:

Analysis of clinical microbiology laboratory testing data from cerebrospinal fluid samples.
Comparison of enteroviral meningitis incidence during the typical peak season (August/September/October) in 2020 versus historical data.

Main Results:

The anticipated peak in enteroviral meningitis cases for August, September, and October did not materialize in 2020.
This represents a significant departure from the established seasonal trend.

Conclusions:

The absence of the typical enteroviral meningitis seasonal peak in 2020 is notable.
Coronavirus disease 2019 (COVID-19) mitigation strategies may have influenced this epidemiological shift.