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Updated: Nov 24, 2025

Hydrodynamic Renal Pelvis Injection for Non-viral Expression of Proteins in the Kidney
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The Vanderbilt O'Brien Kidney Center.

Ambra Pozzi1,2,3, Raymond C Harris1,2,3

  • 1Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee.

American Journal of Physiology. Renal Physiology
|December 28, 2020
PubMed
Summary
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The Vanderbilt O'Brien Kidney Center (VOKC) supports kidney disease research by offering tools and expertise. It facilitates understanding disease mechanisms and developing personalized therapies for better patient outcomes.

Area of Science:

  • Nephrology
  • Translational Research
  • Biomedical Research

Background:

  • The Vanderbilt O'Brien Kidney Center (VOKC) is a National Institutes of Health (NIH) P30-funded center.
  • It is one of eight such centers in the United States dedicated to kidney disease research.

Purpose of the Study:

  • To provide technical and conceptual support for kidney disease research.
  • To facilitate understanding of acute and chronic kidney disease mechanisms.
  • To identify potential therapies for kidney diseases and translate discoveries into personalized care.

Main Methods:

  • Offering expertise in animal model selection, statistical analysis, and clinical study design.
  • Fostering collaborative investigations into critical kidney disease questions.
Keywords:
O’Brien Centercore serviceseducationkidney diseasemouseoutreachpathophysiologypreclinical studiesworkshops

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  • Disseminating information about VOKC services and kidney disease research.

    • Main Results:

    • The VOKC provides state-of-the-art core services.
    • An education and outreach program enhances the study of kidney disease.
    • Information on VOKC services and kidney disease is publicized to researchers and the community.

    Conclusions:

    • The VOKC significantly contributes to advancing kidney disease research and patient care.
    • It serves as a vital resource for the scientific community studying renal diseases.
    • The center promotes collaboration, personalized medicine, and public awareness in nephrology.